2022 Mercedes-Benz S500 Review: 6-Cylinder Serenity

What a beautiful beast.

Daniel Golson/CNET

Luxury automakers are all about more is more, stuffing flagship vehicles with big power, high-end tech features and plenty of gimmicky options. The is no different, with the latest generation being the most extravagant and advanced yet. But I’ll let you in on a secret: The base S500 is where it’s at.


  • Fantastic in-line six engine

  • Supreme comfort

  • Great tech features

Don’t like

  • Misses out on a couple of cool features

The S500 shares its turbocharged, mild-hybrid 3.0-liter in-line six with a number of other Mercedes products. In the S500 it puts out 429 horsepower and 384 pound-feet of torque, with the 48-volt integrated starter/generator system adding an extra boost of 21 hp and 184 lb.-ft. That’s 67 hp and 132 lb.-ft. less than the V8-powered S580, but the S500 feels plenty quick, hitting 60 mph in 4.8 seconds (only 0.4-second slower than the S580). The in-line six is ultra smooth and sounds great, and the nine-speed automatic is smooth. The S500 is efficient, too; I have no trouble matching…

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